1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopropane-1-carboxylic acid, (9H-Fluoren-9-yl)methyl (1-carboxycycloprop-1-yl)carbamate
FMOC-ACPC-OH
CAS: 116857-11-5;126705-22-4
Molecular Formula: C19H17NO4
1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopropane-1-carboxylic acid, (9H-Fluoren-9-yl)methyl (1-carboxycycloprop-1-yl)carbamate - Names and Identifiers
| Name | FMOC-ACPC-OH |
| Synonyms | FMOC-AC3C-OH FMOC-ACPC-OH 1-(Fmoc-amino)cyclopropanecarboxylic acid 1-(FMOC-AMINO)-CYCLOPROPANECARBOXYLIC ACID 1-Aminocyclopropane-1-carboxylic acid, N-FMOC protected 1-(9-FLUORENYLMETHYLOXYCARBONYL-AMINO)-CYCLOPROPYL-1-CARBOXYLIC ACID 1-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}cyclopropanecarboxylic acid 1-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-1-cyclopropanecarboxylic acid 1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopropane-1-carboxylic acid, (9H-Fluoren-9-yl)methyl (1-carboxycycloprop-1-yl)carbamate |
| CAS | 116857-11-5 126705-22-4 |
| InChI | InChI=1/C19H17NO4/c21-17(22)19(9-10-19)20-18(23)24-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2,(H,20,23)(H,21,22) |
1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopropane-1-carboxylic acid, (9H-Fluoren-9-yl)methyl (1-carboxycycloprop-1-yl)carbamate - Physico-chemical Properties
| Molecular Formula | C19H17NO4 |
| Molar Mass | 323.34 |
| Density | 1.39±0.1 g/cm3(Predicted) |
| Melting Point | 225-226 |
| Boling Point | 566.9±29.0 °C(Predicted) |
| Flash Point | 296.7°C |
| Vapor Presure | 1.09E-13mmHg at 25°C |
| Appearance | White powder |
| BRN | 9348574 |
| pKa | 3.97±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.671 |
| MDL | MFCD00190873 |
| Physical and Chemical Properties | Storage Conditions: 2-8 ℃ WGK Germany:3 |
1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopropane-1-carboxylic acid, (9H-Fluoren-9-yl)methyl (1-carboxycycloprop-1-yl)carbamate - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopropane-1-carboxylic acid, (9H-Fluoren-9-yl)methyl (1-carboxycycloprop-1-yl)carbamate - Introduction
1. nature:
1-(N-fluorenylmethoxycarbonylamino) cyclopropanecarboxylic acid is a white to gray solid with a special odor. It is stable at room temperature and soluble in organic solvents such as dimethylformamide (DMF), dichloromethane, etc.
2. use:
1-(N-fluorenylmethoxycarbonylamino) cyclopropanecarboxylic acid is a commonly used protecting group compound, which is often used to protect amino or hydroxyl groups in organic synthesis to prevent them from being affected by other reagents or reaction conditions. It is also commonly used in polymer synthesis, drug synthesis and other fields.
3. Preparation method:
The preparation of 1-(N-fluorenylmethoxycarbonylamino) cyclopropanecarboxylic acid generally employs a series of reaction steps. First, 1-(N-fluorenylmethyloxymethyl) ethylamine was obtained by the reaction of fluorenylmethanol with chloromethyl dimethylcarbamate by synthetic chemical methods. Then, 1-(N-fluorenylmethoxymethyl) ethylamine is reacted with cyclopropanecarboxylic acid by an etherification reaction to give the target product 1-(N-fluorenylmethoxycarbonylamino) cyclopropanecarboxylic acid.
4. Safety Information:
1-(N-fluorenylmethoxycarbonylamino) cyclopropanecarboxylic acid should be handled with caution to avoid contact with skin, eyes and respiratory tract. Always wear personal protective equipment such as lab gloves, goggles, and chemical shields during operation. If exposed, rinse immediately with plenty of water and seek medical assistance.
Last Update：2024-04-09 21:01:54
![1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopropane-1-carboxylic acid, (9H-Fluoren-9-yl)methyl (1-carboxycycloprop-1-yl)carbamate](http://res.chembk.com/assets/images/structure/301779.gif)
Supplier List
Product Name: 1-(Fmoc-amino)cyclopropanecarboxylic acid Visit Supplier Webpage Request for quotation
CAS: 126705-22-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 126705-22-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: 1-(Fmoc-amino)cyclopropanecarboxylic acid Visit Supplier Webpage Request for quotation
CAS: 126705-22-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 126705-22-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History